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Wolverhampton Wanderers welcomes Champions Liverpool to Molineux, where they're hopeful that they can pick up three points against Jurgen Klopp's out-of-form Liverpool side.
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Both teams are hoping that they can finish in the top-four this season. A Manchester United win will put an eleven point gap between them and fifth-placed West Ham. It is a six-point match for the Hammers who have European dreams of their own.
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Southampton takes on south coast rivals Brighton & Home Albion. The Saints’ will be hoping that they can bag all three points.
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Top of the table Manchester City travel to Craven Cottage to take on Fulham who will be hoping that they can jump out of the relegation zone with a win over the league leaders.
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Everton will be hoping that results will go their way, if all goes well they will be within a point of the top-four.
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Crystal Palace takes on struggling West Bromwich Albion.
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This is a game that has goals written all over it. Chelsea will be looking to push themselves into the top three.
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Top of the table Manchester City plays hosts to out of form Southampton.
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Newcastle United invited European hopefuls Aston Villa to St James's Park for what on what paper is a mouth-watering spectacle.
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Brighton welcome Leicester City to the Amex Stadium.
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